High School Students’ Performances in Transitions between Different Representations of Linear Relationships in Mathematics and Physics

This study involved 643 high school students to assess their performance in using different representations of linear functions—graphs, tables, and algebraic relationships—in mathematics and kinematics. The results show that students encounter greater difficulties when they have to interpret representations involving algebraic relations in mathematics. Furthermore, it is shown how the ability to switch from one type of representation to another is influenced by spatial reasoning skills, orientation toward physics, and self-confidence in the field of mathematics and physics. Implications for teaching kinematics and linear functions are briefly discussed

Thermal Relics in Modified Cosmologies: Bounds on Evolution Histories of the Early Universe and Cosmological Boosts for PAMELA

Alternative cosmologies, based on extensions of General Relativity, predict modified thermal histories in the Early Universe during the pre Big Bang Nucleosynthesis (BBN) era, epoch which is not directly constrained by cosmological observations. When the expansion rate is enhanced with respect to the standard case, thermal relics typically decouple with larger relic abundances. The correct value of the relic abundance is therefore obtained for larger annihilation cross--sections, as compared to standard cosmology. A direct consequence is that indirect detection rates are enhanced. Extending previous analyses of ours, we derive updated astrophysical bounds on the dark matter annihilation cross sections and use them to constrain alternative cosmologies in the pre--BBN era. We also determine the characteristics of these alternative cosmologies in order to provide the correct value of relic abundance for a thermal relic for the (large) annihilation cross--section required to explain the PAMELA results on the positron fraction, therefore providing a "cosmological boost" solution to the dark matter interpretation of the PAMELA data.Comment: 19 pages, 27 figures, matches published versio

Constraints on massive gravity theory from big bang nucleosynthesis

The massive gravity cosmology is studied in the scenario of big bang nucleosynthesis. By making use of current bounds on the deviation from the fractional mass, we derive the constraints on the free parameters of the theory. The cosmological consequences of the model are also discussed in the framework of the PAMELA experiment.Comment: 5 page

New Constraints from PAMELA anti-proton data on Annihilating and Decaying Dark Matter

Recently the PAMELA experiment has released its updated anti-proton flux and anti-proton to proton flux ratio data up to energies of ~200GeV. With no clear excess of cosmic ray anti-protons at high energies, one can extend constraints on the production of anti-protons from dark matter. In this letter, we consider both the cases of dark matter annihilating and decaying into standard model particles that produce significant numbers of anti-protons. We provide two sets of constraints on the annihilation cross-sections/decay lifetimes. In the one set of constraints we ignore any source of anti-protons other than dark matter, which give the highest allowed cross-sections/inverse lifetimes. In the other set we include also anti-protons produced in collisions of cosmic rays with interstellar medium nuclei, getting tighter but more realistic constraints on the annihilation cross-sections/decay lifetimes.Comment: 7 pages, 3 figures, 3 table

Small bowel emergency surgery: literature's review

Emergency surgery of the small bowel represents a challenge for the surgeon, in the third millennium as well. There is a wide number of pathologies which involve the small bowel. The present review, by analyzing the recent and past literature, resumes the more commons. The aim of the present review is to provide the main indications to face the principal pathologies an emergency surgeon has to face with during his daily activity

Fermi Gamma-ray Haze via Dark Matter and Millisecond Pulsars

We study possible astrophysical and dark matter (DM) explanations for the Fermi gamma-ray haze in the Milky Way halo. As representatives of various DM models, we consider DM particles annihilating into W+W-, b-bbar, and e+e-. In the first two cases, the prompt gamma-ray emission from DM annihilations is significant or even dominant at E > 10 GeV, while inverse Compton scattering (ICS) from annihilating DM products is insignificant. For the e+e- annihilation mode, we require a boost factor of order 100 to get significant contribution to the gamma-ray haze from ICS photons. Possible astrophysical sources of high energy particles at high latitudes include type Ia supernovae (SNe) and millisecond pulsars (MSPs). Based on our current understanding of Ia SNe rates, they do not contribute significantly to gamma-ray flux in the halo of the Milky Way. As the MSP population in the stellar halo of the Milky Way is not well constrained, MSPs may be a viable source of gamma-rays at high latitudes provided that there are ~ 20 000 - 60 000 of MSPs in the Milky Way stellar halo. In this case, pulsed gamma-ray emission from MSPs can contribute to gamma-rays around few GeV's while the ICS photons from MSP electrons and positrons may be significant at all energies in the gamma-ray haze. The plausibility of such a population of MSPs is discussed. Consistency with the Wilkinson Microwave Anisotropy Probe (WMAP) microwave haze requires that either a significant fraction of MSP spin-down energy is converted into e+e- flux or the DM annihilates predominantly into leptons with a boost factor of order 100.Comment: 18 pages, 1 table, 5 figures; v2: references and a few discussions added, v3: minor change

Association of non-alcoholic fatty liver disease with left ventricular changes in treatment-naive patients with uncomplicated hypertension

Background and aims: Cardiac structural and functional changes have been demonstrated in patients with non-alcoholic fatty liver disease (NAFLD). Because of the frequent association of NAFLD with hypertension, we aimed to examine the relationship of liver steatosis with left ventricular (LV) changes in patients with hypertension. Materials and methods: In a cross-sectional study, we included 360 untreated, essential hypertensive patients who were free of major cardiovascular and renal complications. Liver steatosis was assessed by three different biochemical scores (NAFLD Liver Fat Score, LFS; Fatty Liver Index, FLI; Hepatic Steatosis Index, HSI). Echocardiography was performed with standard B-mode and tissue-Doppler imaging. Results: LV hypertrophy was present in 19.4% and LV diastolic dysfunction in 49.2% of patients who had significantly higher body mass index (BMI), blood pressure (BP), and homeostatic model assessment (HOMA) index and higher frequency of the metabolic syndrome and liver steatosis that was defined by presence of 2 or more positive scores. LV mass index increased progressively across patients who had none, 1, or 2 or more liver steatosis scores, with associated progressive worsening of LV diastolic function. LV mass index was significantly and positively correlated with age, BMI, BP, HOMA-index, LFS, and HSI. Logistic regression analysis showed that age, BP, and liver steatosis scores independently predicted LV hypertrophy and diastolic dysfunction. Liver steatosis independently predicted LV dysfunction but not LV hypertrophy even after inclusion in analysis of the HOMA-index. Conclusion: NAFLD is associated with LV hypertrophy and diastolic dysfunction in untreated patients with hypertension. In hypertension, NAFLD could contribute to LV diastolic dysfunction with mechanisms unrelated to insulin resistance

Executive function abnormalities in pathological gamblers

Background: Pathological gambling (PG) is an impulse control disorder characterized by persistent and maladaptive gambling behaviors with disruptive consequences for familial, occupational and social functions. The pathophysiology of PG is still unclear, but it is hypothesized that it might include environmental factors coupled with a genetic vulnerability and dysfunctions of different neurotransmitters and selected brain areas. Our study aimed to evaluate a group of patients suffering from PG by means of some neuropsychological tests in order to explore the brain areas related to the disorder. Methods: Twenty outpatients (15 men, 5 women), with a diagnosis of PG according to DSM-IV criteria, were included in the study and evaluated with a battery of neuropsychological tests: the Wisconsin Card Sorting Test (WCST), the Wechsler Memory Scale revised (WMS-R) and the Verbal Associative Fluency Test (FAS). The results obtained in the patients were compared with normative values of matched healthy control subjects. Results: The PG patients showed alterations at the WCST only, in particular they had a great difficulty in finding alternative methods of problem-solving and showed a decrease, rather than an increase, in efficiency, as they progressed through the consecutive phases of the test. The mean scores of the other tests were within the normal range. Conclusion: Our findings showed that patients affected by PG, in spite of normal intellectual, linguistic and visual-spatial abilities, had abnormalities emerging from the WCST, in particular they could not learn from their mistakes and look for alternative solutions. Our results would seem to confirm an altered functioning of the prefrontal areas which might provoke a sort of cognitive "rigidity" that might predispose to the development of impulsive and/or compulsive behaviors, such as those typical of PG. © 2008 Marazziti et al; licensee BioMed Central Ltd

Sustained virologic response to direct-acting antiviral agents predicts better outcomes in hepatitis C virus-infected patients: A retrospective study

Direct-acting antiviral agents (DAAs) are extremely effective in eradicating hepatitis C virus (HCV) in chronically infected patients. However, the protective role of the sustained virologic response (SVR) achieved by second- and third-generation DAAs against the onset of hepatocellular carcinoma (HCC) and mortality is less well established